E-Beam Patterned Gold Nanodot Arrays on Optical Fiber Tips for Localized Surface Plasmon Resonance Biochemical Sensing

Electron beam lithography (EBL) was used to directly pattern periodic gold nanodot arrays on optical fiber tips. Localized surface plasmon resonance of the E-beam patterned gold nanodot arrays on optical fiber tips was utilized for biochemical sensing. The advantage of the optical fiber based locali...

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Detalles Bibliográficos
Autores principales: Lin, Yongbin, Zou, Yang, Mo, Yuanyao, Guo, Junpeng, Lindquist, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230952/
https://www.ncbi.nlm.nih.gov/pubmed/22163415
http://dx.doi.org/10.3390/s101009397
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author Lin, Yongbin
Zou, Yang
Mo, Yuanyao
Guo, Junpeng
Lindquist, Robert G.
author_facet Lin, Yongbin
Zou, Yang
Mo, Yuanyao
Guo, Junpeng
Lindquist, Robert G.
author_sort Lin, Yongbin
collection PubMed
description Electron beam lithography (EBL) was used to directly pattern periodic gold nanodot arrays on optical fiber tips. Localized surface plasmon resonance of the E-beam patterned gold nanodot arrays on optical fiber tips was utilized for biochemical sensing. The advantage of the optical fiber based localized surface plasmon resonance (LSPR) sensors is the convenience to work with and work in harsh environments. An optical fiber tip LSPR refractive index sensor of 196 nm per refractive index unit (RIU) sensitivity has been demonstrated. The affinity sensing property of the fiber tip sensor was demonstrated using biotin/streptavidin as the receptor/analyte. The detection limit for streptavidin was determined to be 6 pM.
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spelling pubmed-32309522011-12-07 E-Beam Patterned Gold Nanodot Arrays on Optical Fiber Tips for Localized Surface Plasmon Resonance Biochemical Sensing Lin, Yongbin Zou, Yang Mo, Yuanyao Guo, Junpeng Lindquist, Robert G. Sensors (Basel) Article Electron beam lithography (EBL) was used to directly pattern periodic gold nanodot arrays on optical fiber tips. Localized surface plasmon resonance of the E-beam patterned gold nanodot arrays on optical fiber tips was utilized for biochemical sensing. The advantage of the optical fiber based localized surface plasmon resonance (LSPR) sensors is the convenience to work with and work in harsh environments. An optical fiber tip LSPR refractive index sensor of 196 nm per refractive index unit (RIU) sensitivity has been demonstrated. The affinity sensing property of the fiber tip sensor was demonstrated using biotin/streptavidin as the receptor/analyte. The detection limit for streptavidin was determined to be 6 pM. Molecular Diversity Preservation International (MDPI) 2010-10-20 /pmc/articles/PMC3230952/ /pubmed/22163415 http://dx.doi.org/10.3390/s101009397 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Lin, Yongbin
Zou, Yang
Mo, Yuanyao
Guo, Junpeng
Lindquist, Robert G.
E-Beam Patterned Gold Nanodot Arrays on Optical Fiber Tips for Localized Surface Plasmon Resonance Biochemical Sensing
title E-Beam Patterned Gold Nanodot Arrays on Optical Fiber Tips for Localized Surface Plasmon Resonance Biochemical Sensing
title_full E-Beam Patterned Gold Nanodot Arrays on Optical Fiber Tips for Localized Surface Plasmon Resonance Biochemical Sensing
title_fullStr E-Beam Patterned Gold Nanodot Arrays on Optical Fiber Tips for Localized Surface Plasmon Resonance Biochemical Sensing
title_full_unstemmed E-Beam Patterned Gold Nanodot Arrays on Optical Fiber Tips for Localized Surface Plasmon Resonance Biochemical Sensing
title_short E-Beam Patterned Gold Nanodot Arrays on Optical Fiber Tips for Localized Surface Plasmon Resonance Biochemical Sensing
title_sort e-beam patterned gold nanodot arrays on optical fiber tips for localized surface plasmon resonance biochemical sensing
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230952/
https://www.ncbi.nlm.nih.gov/pubmed/22163415
http://dx.doi.org/10.3390/s101009397
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