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Integrating transcriptomics and metabonomics to unravel modes-of-action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in HepG2 cells

BACKGROUND: The integration of different 'omics' technologies has already been shown in several in vivo studies to offer a complementary insight into cellular responses to toxic challenges. Being interested in developing in vitro cellular models as alternative to animal-based toxicity assa...

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Detalles Bibliográficos
Autores principales:	Jennen, Danyel, Ruiz-Aracama, Ainhoa, Magkoufopoulou, Christina, Peijnenburg, Ad, Lommen, Arjen, van Delft, Joost, Kleinjans, Jos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3231768/ https://www.ncbi.nlm.nih.gov/pubmed/21880148 http://dx.doi.org/10.1186/1752-0509-5-139

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