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Seleno-detergent MAD phasing of leukotriene C(4) synthase in complex with dodecyl-β-d-selenomaltoside

Dodecyl-β-d-selenomaltoside (SeDDM) is a seleno-detergent with a β-glycosidic seleno-ether in place of the ether moiety in dodecyl-β-d-maltoside. Seleno-detergents are candidates for heavy-atom agents in experimental phasing of membrane proteins in protein crystallography. Crystals of a nuclear memb...

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Detalles Bibliográficos
Autores principales: Saino, Hiromichi, Ago, Hideo, Ukita, Yoko, Miyano, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232166/
https://www.ncbi.nlm.nih.gov/pubmed/22139193
http://dx.doi.org/10.1107/S1744309111042345