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MicroRNA-Driven Developmental Remodeling in the Brain Distinguishes Humans from Other Primates
While multiple studies have reported the accelerated evolution of brain gene expression in the human lineage, the mechanisms underlying such changes are unknown. Here, we address this issue from a developmental perspective, by analyzing mRNA and microRNA (miRNA) expression in two brain regions withi...
Autores principales: | Somel, Mehmet, Liu, Xiling, Tang, Lin, Yan, Zheng, Hu, Haiyang, Guo, Song, Jiang, Xi, Zhang, Xiaoyu, Xu, Guohua, Xie, Gangcai, Li, Na, Hu, Yuhui, Chen, Wei, Pääbo, Svante, Khaitovich, Philipp |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232219/ https://www.ncbi.nlm.nih.gov/pubmed/22162950 http://dx.doi.org/10.1371/journal.pbio.1001214 |
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