IL-1α/IL-1R1 Expression in Chronic Obstructive Pulmonary Disease and Mechanistic Relevance to Smoke-Induced Neutrophilia in Mice

BACKGROUND: Cigarette smoking is the main risk factor for the development of chronic obstructive pulmonary disease (COPD), a major cause of morbidity and mortality worldwide. Despite this, the cellular and molecular mechanisms that contribute to COPD pathogenesis are still poorly understood. METHODO...

Descripción completa

Detalles Bibliográficos
Autores principales: Botelho, Fernando M., Bauer, Carla M. T., Finch, Donna, Nikota, Jake K., Zavitz, Caleb C. J., Kelly, Ashling, Lambert, Kristen N., Piper, Sian, Foster, Martyn L., Goldring, James J. P., Wedzicha, Jadwiga A., Bassett, Jennifer, Bramson, Jonathan, Iwakura, Yoichiro, Sleeman, Matthew, Kolbeck, Roland, Coyle, Anthony J., Humbles, Alison A., Stämpfli, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232226/
https://www.ncbi.nlm.nih.gov/pubmed/22163019
http://dx.doi.org/10.1371/journal.pone.0028457

Ejemplares similares

Ejemplares similares