Cargando…

Non congenital heart disease aspects of Down's syndrome

Down's syndrome is the commonest chromosomal anomaly with an incidence of about 1:700 live births, and is often associated with various congenital anomalies. Moreover an appreciable proportion of health problems (immunological, hematological, etc) are frequently associated with this condition,...

Descripción completa

Detalles Bibliográficos
Autor principal: Bianca, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232533/
https://www.ncbi.nlm.nih.gov/pubmed/22368619
_version_ 1782218370965307392
author Bianca, S
author_facet Bianca, S
author_sort Bianca, S
collection PubMed
description Down's syndrome is the commonest chromosomal anomaly with an incidence of about 1:700 live births, and is often associated with various congenital anomalies. Moreover an appreciable proportion of health problems (immunological, hematological, etc) are frequently associated with this condition, and for this reason affected individuals benefit greatly from multidisciplinary management. Recent research strongly suggests that Down's syndrome is a contiguous gene syndrome, and it is unlikely that a single Down's syndrome chromosomal region is responsible for the typical phenotypic features. This review presents the most important genetic and medical features.
format Online
Article
Text
id pubmed-3232533
institution National Center for Biotechnology Information
language English
publishDate 2002
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-32325332012-02-22 Non congenital heart disease aspects of Down's syndrome Bianca, S Images Paediatr Cardiol Invited Article Down's syndrome is the commonest chromosomal anomaly with an incidence of about 1:700 live births, and is often associated with various congenital anomalies. Moreover an appreciable proportion of health problems (immunological, hematological, etc) are frequently associated with this condition, and for this reason affected individuals benefit greatly from multidisciplinary management. Recent research strongly suggests that Down's syndrome is a contiguous gene syndrome, and it is unlikely that a single Down's syndrome chromosomal region is responsible for the typical phenotypic features. This review presents the most important genetic and medical features. Medknow Publications & Media Pvt Ltd 2002 /pmc/articles/PMC3232533/ /pubmed/22368619 Text en Copyright: © Images in Paediatric Cardiology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Invited Article
Bianca, S
Non congenital heart disease aspects of Down's syndrome
title Non congenital heart disease aspects of Down's syndrome
title_full Non congenital heart disease aspects of Down's syndrome
title_fullStr Non congenital heart disease aspects of Down's syndrome
title_full_unstemmed Non congenital heart disease aspects of Down's syndrome
title_short Non congenital heart disease aspects of Down's syndrome
title_sort non congenital heart disease aspects of down's syndrome
topic Invited Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232533/
https://www.ncbi.nlm.nih.gov/pubmed/22368619
work_keys_str_mv AT biancas noncongenitalheartdiseaseaspectsofdownssyndrome