Functional analysis of the Hsf4(lop11) allele responsible for cataracts in lop11 mice

PURPOSE: Lens opacity 11 (lop11) is a spontaneous autosomal recessive mouse mutation resulting in cataracts. Insertion of an early transposable element (ETn) in intron 9 of heat shock factor 4 (Hsf4) was previously identified as responsible for lop11 cataracts. Although molecular analysis showed tha...

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Detalles Bibliográficos
Autores principales: Liang, Lina, Liegel, Ryan, Endres, Brad, Ronchetti, Adam, Chang, Bo, Sidjanin, D.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233385/
https://www.ncbi.nlm.nih.gov/pubmed/22162625

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