Cargando…
IL-17A stimulates the production of inflammatory mediators via Erk1/2, p38 MAPK, PI3K/Akt, and NF-κB pathways in ARPE-19 cells
PURPOSE: To investigate the signaling pathways involved in interleukin (IL)-17A -mediated production of interleukin 8 (CXCL8), chemokine (C-C motif) ligand 2 (CCL2), and interleukin 6 (IL-6) by ARPE-19 cells, a spontaneously arisen cell line of retinal pigment epithelium (RPE). METHODS: Flow cytomet...
Autores principales: | Chen, Ying, Kijlstra, Aize, Chen, Yuanyuan, Yang, Peizeng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233389/ https://www.ncbi.nlm.nih.gov/pubmed/22162626 |
Ejemplares similares
-
The Effects of Th17 Cytokines on the Inflammatory Mediator Production and Barrier Function of ARPE-19 Cells
por: Chen, Ying, et al.
Publicado: (2011) -
IL-8 promotes inflammatory mediators and stimulates activation of p38 MAPK/ERK-NF-κB pathway and reduction of JNK in HNSCC
por: Chan, Leong-Perng, et al.
Publicado: (2017) -
P38/ERK MAPK signaling pathways are involved in the regulation of filaggrin and involucrin by IL-17
por: Tan, Qi, et al.
Publicado: (2017) -
IFN-β Inhibits the Increased Expression of IL-9 during Experimental Autoimmune Uveoretinitis
por: Yang, Yan, et al.
Publicado: (2012) -
Downregulating p22phox ameliorates inflammatory response in Angiotensin II-induced oxidative stress by regulating MAPK and NF-κB pathways in ARPE-19 cells
por: Qiu, Yiguo, et al.
Publicado: (2015)