Cargando…

Antiproliferative Effect of Aaptamine on Human Chronic Myeloid Leukemia K562 Cells

We previously isolated aaptamine, a benzonaphthyridine alkaloid, from marine sponge Aaptos suberitoids. In this study, we investigated the anti-proliferative effect of aaptamine on chronic myeloid leukemia (CML) K562 cells. Aaptamine inhibited growth of K562 with a GI50 as 10 μM, and arrested cell c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jin, Meihua, Zhao, Wennan, Zhang, Yanwen, Kobayashi, Motomasa, Duan, Hongquan, Kong, Dexin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233409/ https://www.ncbi.nlm.nih.gov/pubmed/22174603 http://dx.doi.org/10.3390/ijms12117352

Ejemplares similares

Antiproliferative and Antiangiogenic Activities of Smenospongine, a Marine Sponge Sesquiterpene Aminoquinone
por: Kong, Dexin, et al.
Publicado: (2011)

In Vitro Antileukemia Activity of ZSTK474 on K562 and Multidrug Resistant K562/A02 Cells
por: Zhou, Qianxiang, et al.
Publicado: (2016)

Anticancer activity of Pupalia lappacea on chronic myeloid leukemia K562 cells
por: Ravi, Alvala, et al.
Publicado: (2012)

Tendency of K562 Chronic Myeloid Leukemia Cells Towards Cell Reprogramming
por: Yılmazer Aktuna, Açelya
Publicado: (2018)

A Central Contribution of TG2 Activity to the Antiproliferative and Pro-Apoptotic Effects of Caffeic Acid in K562 Cells of Human Chronic Myeloid Leukemia
por: Feriotto, Giordana, et al.
Publicado: (2022)

CDA gene silencing regulated the proliferation and apoptosis of chronic myeloid leukemia K562 cells
por: Wei, Xiao-Fang, et al.
Publicado: (2018)

Inhibitory Activity of Flavonoids against Class I Phosphatidylinositol 3-Kinase Isoforms
por: Kong, Dexin, et al.
Publicado: (2011)

Cytotoxic Aaptamines from Malaysian Aaptos aaptos
por: Shaari, Khozirah, et al.
Publicado: (2008)

The Effect of Polyhydroxy Fullerene Derivative on Human Myeloid Leukemia K562 Cells
por: Guo, Wei, et al.
Publicado: (2022)

Induction of human chronic myeloid leukemia K562 cell apoptosis by virosecurinine and its molecular mechanism
por: ZHANG, GANG, et al.
Publicado: (2014)

Growth inhibitory effects of crude pomegranate peel extract on chronic myeloid leukemia, K562 cells
por: Asmaa, Mat Jusoh Siti, et al.
Publicado: (2015)

Cytotoxic effect of sea anemone pore-forming toxin on K562 chronic myeloid leukemia cells
por: Abdoli, Vali, et al.
Publicado: (2021)

Proteome Changes Induced by Imatinib and Novel Imatinib Derivatives in K562 Human Chronic Myeloid Leukemia Cells
por: Arvaniti, Katerina, et al.
Publicado: (2014)

The miR-203a Regulatory Network Affects the Proliferation of Chronic Myeloid Leukemia K562 Cells
por: He, Jinhua, et al.
Publicado: (2021)

Vitamin E TPGS 1000 Induces Apoptosis in the K562 Cell Line: Implications for Chronic Myeloid Leukemia
por: Calvo-Alvarez, Jazmin, et al.
Publicado: (2021)

ND-09 inhibits chronic myeloid leukemia K562 cell growth by regulating BCR-ABL signaling
por: Liu, Yan-Hong, et al.
Publicado: (2021)

Gene Expression Landscape of Chronic Myeloid Leukemia K562 Cells Overexpressing the Tumor Suppressor Gene PTPRG
por: Lombardi, Giulia, et al.
Publicado: (2022)

C(5) modified uracil derivatives showing antiproliferative and erythroid differentiation inducing activities on human chronic myelogenous leukemia K562 cells
por: Brognara, Eleonora, et al.
Publicado: (2011)

Transferred BCR/ABL DNA from K562 Extracellular Vesicles Causes Chronic Myeloid Leukemia in Immunodeficient Mice
por: Cai, Jin, et al.
Publicado: (2014)

Stellettin B induces apoptosis in human chronic myeloid leukemia cells via targeting PI3K and Stat5
por: Chen, Yali, et al.
Publicado: (2017)

Proliferation-Attenuating and Apoptosis-Inducing Effects of Tryptanthrin on Human Chronic Myeloid Leukemia K562 Cell Line in Vitro
por: Miao, Shan, et al.
Publicado: (2011)

Induction of apoptosis by Cordyceps militaris fraction in human chronic myeloid leukemia K562 cells involved with mitochondrial dysfunction
por: Tian, Tian, et al.
Publicado: (2014)

Time-series analysis in imatinib-resistant chronic myeloid leukemia K562-cells under different drug treatments
por: Zhao, Yan-hong, et al.
Publicado: (2017)

Artesunate enhances adriamycin cytotoxicity by inhibiting glycolysis in adriamycin-resistant chronic myeloid leukemia K562/ADR cells
por: Chen, Li, et al.
Publicado: (2019)

Cytotoxicity of Isoxazole Curcumin Analogs on Chronic Myeloid Leukemia-Derived K562 Cell Lines Sensitive and Resistant to Imatinib
por: Feriotto, Giordana, et al.
Publicado: (2023)

[Corrigendum] ND‑09 inhibits chronic myeloid leukemia K562 cell growth by regulating BCR‑ABL signaling
por: Liu, Yan-Hong, et al.
Publicado: (2023)

Role of Calcium-Activated Potassium Channels in Proliferation, Migration and Invasion of Human Chronic Myeloid Leukemia K562 Cells
por: Vasileva, Valeria Y., et al.
Publicado: (2023)

MiR-370 sensitizes chronic myeloid leukemia K562 cells to homoharringtonine by targeting Forkhead box M1
por: Zhou, MinRan, et al.
Publicado: (2013)

Antiproliferative chromone derivatives induce K562 cell death through endogenous and exogenous pathways
por: Jiao, Runwei, et al.
Publicado: (2020)

New Imatinib Derivatives with Antiproliferative Activity against A549 and K562 Cancer Cells
por: Oliveira, Andressa, et al.
Publicado: (2022)

Atorvastatin Exerts Antileukemia Activity via Inhibiting Mevalonate-YAP Axis in K562 and HL60 Cells
por: Zhang, Lei, et al.
Publicado: (2019)

Aaptamine attenuates the proliferation and progression of non-small cell lung carcinoma
por: Gong, Kaikai, et al.
Publicado: (2020)

Antinociceptive Effects of Aaptamine, a Sponge Component, on Peripheral Neuropathy in Rats
por: Sung, Chun-Sung, et al.
Publicado: (2023)

Aclacinomycin A Sensitizes K562 Chronic Myeloid Leukemia Cells to Imatinib through p38MAPK-Mediated Erythroid Differentiation
por: Lee, Yueh-Lun, et al.
Publicado: (2013)

Tuberostemonine reverses multidrug resistance in chronic myelogenous leukemia cells K562/ADR
por: Wang, Yu Jia, et al.
Publicado: (2017)

Ketoconazole Reverses Imatinib Resistance in Human Chronic Myelogenous Leukemia K562 Cells
por: Prado-Carrillo, Omar, et al.
Publicado: (2022)

Smenospongine, a Sesquiterpene Aminoquinone from a Marine Sponge, Induces G1 Arrest or Apoptosis in Different Leukemia Cells
por: Kong, Dexin, et al.
Publicado: (2008)

Correction: Aclacinomycin A Sensitizes K562 Chronic Myeloid Leukemia Cells to Imatinib through p38MAPK-Mediated Erythroid Differentiation
por: Lee, Yueh-Lun, et al.
Publicado: (2017)

Cytotoxic Effects of Some Flavonoids and Imatinib on the K562 Chronic Myeloid Leukemia Cell Line: Data Analysis Using the Combination Index Method
por: Danışman Kalındemirtaş, Ferdane, et al.
Publicado: (2019)

Thymoquinone Enhances Apoptosis of K562 Chronic Myeloid Leukemia Cells through Hypomethylation of SHP-1 and Inhibition of JAK/STAT Signaling Pathway
por: Al-Rawashde, Futoon Abedrabbu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_21r5o39t97g4sag7pati6cs0d4