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Impact of Host Cell Line Adaptation on Quasispecies Composition and Glycosylation of Influenza A Virus Hemagglutinin

The genome of influenza A viruses is constantly changing (genetic drift) resulting in small, gradual changes in viral proteins. Alterations within antibody recognition sites of the viral membrane glycoproteins hemagglutinin (HA) and neuraminidase (NA) result in an antigenetic drift, which requires t...

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Detalles Bibliográficos
Autores principales:	Roedig, Jana Verena, Rapp, Erdmann, Höper, Dirk, Genzel, Yvonne, Reichl, Udo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233551/ https://www.ncbi.nlm.nih.gov/pubmed/22163276 http://dx.doi.org/10.1371/journal.pone.0027989

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