Functional and Transcriptional Induction of Aquaporin-1 Gene by Hypoxia; Analysis of Promoter and Role of Hif-1α

Aquaporin-1 (AQP1) is a water channel that is highly expressed in tissues with rapid O(2) transport. It has been reported that this protein contributes to gas permeation (CO(2), NO and O(2)) through the plasma membrane. We show that hypoxia increases Aqp1 mRNA and protein levels in tissues, namely m...

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Detalles Bibliográficos
Autores principales: Abreu-Rodríguez, Irene, Sánchez Silva, Rocío, Martins, Ana Paula, Soveral, Graça, Toledo-Aral, Juan José, López-Barneo, José, Echevarría, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233559/
https://www.ncbi.nlm.nih.gov/pubmed/22174795
http://dx.doi.org/10.1371/journal.pone.0028385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233559/
https://www.ncbi.nlm.nih.gov/pubmed/22174795
http://dx.doi.org/10.1371/journal.pone.0028385

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