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Impact of the Lectin Chaperone Calnexin on the Stress Response, Virulence and Proteolytic Secretome of the Fungal Pathogen Aspergillus fumigatus
Calnexin is a membrane-bound lectin chaperone in the endoplasmic reticulum (ER) that is part of a quality control system that promotes the accurate folding of glycoproteins entering the secretory pathway. We have previously shown that ER homeostasis is important for virulence of the human fungal pat...
Autores principales: | Powers-Fletcher, Margaret V., Jambunathan, Kalyani, Brewer, Jordan L., Krishnan, Karthik, Feng, Xizhi, Galande, Amit K., Askew, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233604/ https://www.ncbi.nlm.nih.gov/pubmed/22163332 http://dx.doi.org/10.1371/journal.pone.0028865 |
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