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Might salicylate exert benefits against childhood cancer?

Childhood cancers are a broad range of diseases. Research on the chemopreventive potential of non-steroidal anti-inflammatory drugs, such as aspirin (acetylsalicylate) has yet to be fully directed towards childhood cancers. A prima facie hypothesis on salicylate and childhood cancer would therefore...

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Detalles Bibliográficos
Autores principales: Morgan, G, Johnsen, JI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234022/
https://www.ncbi.nlm.nih.gov/pubmed/22276025
http://dx.doi.org/10.3332/ecancer.2010.156
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author Morgan, G
Johnsen, JI
author_facet Morgan, G
Johnsen, JI
author_sort Morgan, G
collection PubMed
description Childhood cancers are a broad range of diseases. Research on the chemopreventive potential of non-steroidal anti-inflammatory drugs, such as aspirin (acetylsalicylate) has yet to be fully directed towards childhood cancers. A prima facie hypothesis on salicylate and childhood cancer would therefore be based on several factors. Firstly, salicylate inhibits the production of inflammatory prostaglandins, which have been shown to stimulate the growth of cancer cells. Secondly, salicylate inhibits the growth of cancer cells in pre-clinical models. Thirdly, salicylate is a natural component of fruits and vegetables so it is consumed within the diet. Further research, of which some possibilities are identified, is recommended.
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spelling pubmed-32340222012-01-24 Might salicylate exert benefits against childhood cancer? Morgan, G Johnsen, JI Ecancermedicalscience Reviews Childhood cancers are a broad range of diseases. Research on the chemopreventive potential of non-steroidal anti-inflammatory drugs, such as aspirin (acetylsalicylate) has yet to be fully directed towards childhood cancers. A prima facie hypothesis on salicylate and childhood cancer would therefore be based on several factors. Firstly, salicylate inhibits the production of inflammatory prostaglandins, which have been shown to stimulate the growth of cancer cells. Secondly, salicylate inhibits the growth of cancer cells in pre-clinical models. Thirdly, salicylate is a natural component of fruits and vegetables so it is consumed within the diet. Further research, of which some possibilities are identified, is recommended. Cancer Intelligence 2010-01-19 /pmc/articles/PMC3234022/ /pubmed/22276025 http://dx.doi.org/10.3332/ecancer.2010.156 Text en © the authors; licensee ecancermedicalscience. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Morgan, G
Johnsen, JI
Might salicylate exert benefits against childhood cancer?
title Might salicylate exert benefits against childhood cancer?
title_full Might salicylate exert benefits against childhood cancer?
title_fullStr Might salicylate exert benefits against childhood cancer?
title_full_unstemmed Might salicylate exert benefits against childhood cancer?
title_short Might salicylate exert benefits against childhood cancer?
title_sort might salicylate exert benefits against childhood cancer?
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234022/
https://www.ncbi.nlm.nih.gov/pubmed/22276025
http://dx.doi.org/10.3332/ecancer.2010.156
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