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Might salicylate exert benefits against childhood cancer?
Childhood cancers are a broad range of diseases. Research on the chemopreventive potential of non-steroidal anti-inflammatory drugs, such as aspirin (acetylsalicylate) has yet to be fully directed towards childhood cancers. A prima facie hypothesis on salicylate and childhood cancer would therefore...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cancer Intelligence
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234022/ https://www.ncbi.nlm.nih.gov/pubmed/22276025 http://dx.doi.org/10.3332/ecancer.2010.156 |
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author | Morgan, G Johnsen, JI |
author_facet | Morgan, G Johnsen, JI |
author_sort | Morgan, G |
collection | PubMed |
description | Childhood cancers are a broad range of diseases. Research on the chemopreventive potential of non-steroidal anti-inflammatory drugs, such as aspirin (acetylsalicylate) has yet to be fully directed towards childhood cancers. A prima facie hypothesis on salicylate and childhood cancer would therefore be based on several factors. Firstly, salicylate inhibits the production of inflammatory prostaglandins, which have been shown to stimulate the growth of cancer cells. Secondly, salicylate inhibits the growth of cancer cells in pre-clinical models. Thirdly, salicylate is a natural component of fruits and vegetables so it is consumed within the diet. Further research, of which some possibilities are identified, is recommended. |
format | Online Article Text |
id | pubmed-3234022 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Cancer Intelligence |
record_format | MEDLINE/PubMed |
spelling | pubmed-32340222012-01-24 Might salicylate exert benefits against childhood cancer? Morgan, G Johnsen, JI Ecancermedicalscience Reviews Childhood cancers are a broad range of diseases. Research on the chemopreventive potential of non-steroidal anti-inflammatory drugs, such as aspirin (acetylsalicylate) has yet to be fully directed towards childhood cancers. A prima facie hypothesis on salicylate and childhood cancer would therefore be based on several factors. Firstly, salicylate inhibits the production of inflammatory prostaglandins, which have been shown to stimulate the growth of cancer cells. Secondly, salicylate inhibits the growth of cancer cells in pre-clinical models. Thirdly, salicylate is a natural component of fruits and vegetables so it is consumed within the diet. Further research, of which some possibilities are identified, is recommended. Cancer Intelligence 2010-01-19 /pmc/articles/PMC3234022/ /pubmed/22276025 http://dx.doi.org/10.3332/ecancer.2010.156 Text en © the authors; licensee ecancermedicalscience. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Reviews Morgan, G Johnsen, JI Might salicylate exert benefits against childhood cancer? |
title | Might salicylate exert benefits against childhood cancer? |
title_full | Might salicylate exert benefits against childhood cancer? |
title_fullStr | Might salicylate exert benefits against childhood cancer? |
title_full_unstemmed | Might salicylate exert benefits against childhood cancer? |
title_short | Might salicylate exert benefits against childhood cancer? |
title_sort | might salicylate exert benefits against childhood cancer? |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234022/ https://www.ncbi.nlm.nih.gov/pubmed/22276025 http://dx.doi.org/10.3332/ecancer.2010.156 |
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