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Defeating cancer with antidepressants

Prostaglandins are ephemeral, infinitesimal signallers self-regulating every cell in the body, including those sub-serving mood and immunity. At first, they were perceived as a master switch, but now are believed to regulate every component of cellular micro-anatomy and physiology, including those o...

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Detalles Bibliográficos
Autor principal: Lieb, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234054/
https://www.ncbi.nlm.nih.gov/pubmed/22275973
http://dx.doi.org/10.3332/ecancer.2008.88
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author Lieb, J
author_facet Lieb, J
author_sort Lieb, J
collection PubMed
description Prostaglandins are ephemeral, infinitesimal signallers self-regulating every cell in the body, including those sub-serving mood and immunity. At first, they were perceived as a master switch, but now are believed to regulate every component of cellular micro-anatomy and physiology, including those of the organelles, cytoskeleton, proteins, enzymes, nucleic acids and mitochondria. Prostaglandins are responsible, paradoxically, for cell function and dysfunction. Excessive prostaglandin synthesis depresses immune function and may induce cancer. An ideal anti-cancer agent would inhibit prostaglandins in such a manner as to shut down the pathogenesis of cancer. In this paper, I will show that antidepressants have such properties.
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spelling pubmed-32340542012-01-24 Defeating cancer with antidepressants Lieb, J Ecancermedicalscience Research Article Prostaglandins are ephemeral, infinitesimal signallers self-regulating every cell in the body, including those sub-serving mood and immunity. At first, they were perceived as a master switch, but now are believed to regulate every component of cellular micro-anatomy and physiology, including those of the organelles, cytoskeleton, proteins, enzymes, nucleic acids and mitochondria. Prostaglandins are responsible, paradoxically, for cell function and dysfunction. Excessive prostaglandin synthesis depresses immune function and may induce cancer. An ideal anti-cancer agent would inhibit prostaglandins in such a manner as to shut down the pathogenesis of cancer. In this paper, I will show that antidepressants have such properties. Cancer Intelligence 2008-08-21 /pmc/articles/PMC3234054/ /pubmed/22275973 http://dx.doi.org/10.3332/ecancer.2008.88 Text en Copyright: © the authors; licensee ecancermedicalscience. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Lieb, J
Defeating cancer with antidepressants
title Defeating cancer with antidepressants
title_full Defeating cancer with antidepressants
title_fullStr Defeating cancer with antidepressants
title_full_unstemmed Defeating cancer with antidepressants
title_short Defeating cancer with antidepressants
title_sort defeating cancer with antidepressants
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234054/
https://www.ncbi.nlm.nih.gov/pubmed/22275973
http://dx.doi.org/10.3332/ecancer.2008.88
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