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Defeating cancer with antidepressants
Prostaglandins are ephemeral, infinitesimal signallers self-regulating every cell in the body, including those sub-serving mood and immunity. At first, they were perceived as a master switch, but now are believed to regulate every component of cellular micro-anatomy and physiology, including those o...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cancer Intelligence
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234054/ https://www.ncbi.nlm.nih.gov/pubmed/22275973 http://dx.doi.org/10.3332/ecancer.2008.88 |
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author | Lieb, J |
author_facet | Lieb, J |
author_sort | Lieb, J |
collection | PubMed |
description | Prostaglandins are ephemeral, infinitesimal signallers self-regulating every cell in the body, including those sub-serving mood and immunity. At first, they were perceived as a master switch, but now are believed to regulate every component of cellular micro-anatomy and physiology, including those of the organelles, cytoskeleton, proteins, enzymes, nucleic acids and mitochondria. Prostaglandins are responsible, paradoxically, for cell function and dysfunction. Excessive prostaglandin synthesis depresses immune function and may induce cancer. An ideal anti-cancer agent would inhibit prostaglandins in such a manner as to shut down the pathogenesis of cancer. In this paper, I will show that antidepressants have such properties. |
format | Online Article Text |
id | pubmed-3234054 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | Cancer Intelligence |
record_format | MEDLINE/PubMed |
spelling | pubmed-32340542012-01-24 Defeating cancer with antidepressants Lieb, J Ecancermedicalscience Research Article Prostaglandins are ephemeral, infinitesimal signallers self-regulating every cell in the body, including those sub-serving mood and immunity. At first, they were perceived as a master switch, but now are believed to regulate every component of cellular micro-anatomy and physiology, including those of the organelles, cytoskeleton, proteins, enzymes, nucleic acids and mitochondria. Prostaglandins are responsible, paradoxically, for cell function and dysfunction. Excessive prostaglandin synthesis depresses immune function and may induce cancer. An ideal anti-cancer agent would inhibit prostaglandins in such a manner as to shut down the pathogenesis of cancer. In this paper, I will show that antidepressants have such properties. Cancer Intelligence 2008-08-21 /pmc/articles/PMC3234054/ /pubmed/22275973 http://dx.doi.org/10.3332/ecancer.2008.88 Text en Copyright: © the authors; licensee ecancermedicalscience. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Lieb, J Defeating cancer with antidepressants |
title | Defeating cancer with antidepressants |
title_full | Defeating cancer with antidepressants |
title_fullStr | Defeating cancer with antidepressants |
title_full_unstemmed | Defeating cancer with antidepressants |
title_short | Defeating cancer with antidepressants |
title_sort | defeating cancer with antidepressants |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234054/ https://www.ncbi.nlm.nih.gov/pubmed/22275973 http://dx.doi.org/10.3332/ecancer.2008.88 |
work_keys_str_mv | AT liebj defeatingcancerwithantidepressants |