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Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae

Microalgae have presented themselves as a strong candidate to replace diminishing oil reserves as a source of lipids for biofuels. Here we describe successful modifications of terrestrial plant lipid content which increase overall lipid production or shift the balance of lipid production towards lip...

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Autores principales: Yu, Wei-Luen, Ansari, William, Schoepp, Nathan G, Hannon, Michael J, Mayfield, Stephen P, Burkart, Michael D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234195/
https://www.ncbi.nlm.nih.gov/pubmed/22047615
http://dx.doi.org/10.1186/1475-2859-10-91
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author Yu, Wei-Luen
Ansari, William
Schoepp, Nathan G
Hannon, Michael J
Mayfield, Stephen P
Burkart, Michael D
author_facet Yu, Wei-Luen
Ansari, William
Schoepp, Nathan G
Hannon, Michael J
Mayfield, Stephen P
Burkart, Michael D
author_sort Yu, Wei-Luen
collection PubMed
description Microalgae have presented themselves as a strong candidate to replace diminishing oil reserves as a source of lipids for biofuels. Here we describe successful modifications of terrestrial plant lipid content which increase overall lipid production or shift the balance of lipid production towards lipid varieties more useful for biofuel production. Our discussion ranges from the biosynthetic pathways and rate limiting steps of triacylglycerol formation to enzymes required for the formation of triacylglycerol containing exotic lipids. Secondarily, we discuss techniques for genetic engineering and modification of various microalgae which can be combined with insights gained from research in higher plants to aid in the creation of production strains of microalgae.
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spelling pubmed-32341952011-12-09 Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae Yu, Wei-Luen Ansari, William Schoepp, Nathan G Hannon, Michael J Mayfield, Stephen P Burkart, Michael D Microb Cell Fact Review Microalgae have presented themselves as a strong candidate to replace diminishing oil reserves as a source of lipids for biofuels. Here we describe successful modifications of terrestrial plant lipid content which increase overall lipid production or shift the balance of lipid production towards lipid varieties more useful for biofuel production. Our discussion ranges from the biosynthetic pathways and rate limiting steps of triacylglycerol formation to enzymes required for the formation of triacylglycerol containing exotic lipids. Secondarily, we discuss techniques for genetic engineering and modification of various microalgae which can be combined with insights gained from research in higher plants to aid in the creation of production strains of microalgae. BioMed Central 2011-11-02 /pmc/articles/PMC3234195/ /pubmed/22047615 http://dx.doi.org/10.1186/1475-2859-10-91 Text en Copyright ©2011 Yu et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Yu, Wei-Luen
Ansari, William
Schoepp, Nathan G
Hannon, Michael J
Mayfield, Stephen P
Burkart, Michael D
Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae
title Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae
title_full Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae
title_fullStr Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae
title_full_unstemmed Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae
title_short Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae
title_sort modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234195/
https://www.ncbi.nlm.nih.gov/pubmed/22047615
http://dx.doi.org/10.1186/1475-2859-10-91
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