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Role of Collagens and Perlecan in Microvascular Stability: Exploring the Mechanism of Capillary Vessel Damage by Snake Venom Metalloproteinases
Hemorrhage is a clinically important manifestation of viperid snakebite envenomings, and is induced by snake venom metalloproteinases (SVMPs). Hemorrhagic and non-hemorrhagic SVMPs hydrolyze some basement membrane (BM) and associated extracellular matrix (ECM) proteins. Nevertheless, only hemorrhagi...
Autores principales: | Escalante, Teresa, Ortiz, Natalia, Rucavado, Alexandra, Sanchez, Eladio F., Richardson, Michael, Fox, Jay W., Gutiérrez, José María |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234262/ https://www.ncbi.nlm.nih.gov/pubmed/22174764 http://dx.doi.org/10.1371/journal.pone.0028017 |
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