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First Steps Towards an Understanding of a Mode ofCarcinogenic Action for Vanadium Pentoxide

Inhalation of vanadium pentoxide clearly increases the incidence of alveolar/bronchiolar neoplasms in male and female B6C3F1 mice at all concentrations tested (1, 2 or 4 mg/m(3)), whereas responses in F344/N rats was, at most, ambiguous. While vanadium pentoxide is mutagenic in vitro and possibly in...

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Detalles Bibliográficos
Autores principales: Schuler, Detlef, Chevalier, Hans-Jörg, Merker, Mandy, Morgenthal, Katja, Ravanat, Jean-Luc, Sagelsdorff, Peter, Walter, Marc, Weber, Klaus, Mcgregor, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Toxicologic Pathology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234591/
https://www.ncbi.nlm.nih.gov/pubmed/22272055
http://dx.doi.org/10.1293/tox.24.149