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Comparative Nephrotoxicity of Cisplatin and Nedaplatin: Mechanisms and Histopathological Characteristics

The antineoplastic platinum complexes cisplatin and its analogues are widely used in the chemotherapy of a variety of human malignancies, and are especially active against several types of cancers. Nedaplatin is a second-generation platinum complex with reduced nephrotoxicity. However, their use com...

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Detalles Bibliográficos
Autores principales: Uehara, Takeki, Yamate, Jyoji, Torii, Mikinori, Maruyama, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Toxicologic Pathology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234610/
https://www.ncbi.nlm.nih.gov/pubmed/22272048
http://dx.doi.org/10.1293/tox.24.87