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Evaluation of Bone Toxicity in Various Bones of Aged Rats

The aim of the present study was to provide a method for evaluating bone toxicity induced by drugs in various bones in aged rats. Male Crl:CD (SD) rats at 46 weeks of age were administered 15 mg/m(2) body surface area of doxorubicin, which effects the growth plate in weanling rats, weekly for 9 week...

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Detalles Bibliográficos
Autores principales: Noguchi, Chihiro, Miyata, Hiroto, Sato, Yasushi, Iwaki, Yoshinobu, Okuyama, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Toxicologic Pathology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234621/
https://www.ncbi.nlm.nih.gov/pubmed/22272043
http://dx.doi.org/10.1293/tox.24.41

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