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Metabolic Fingerprinting in Toxicological Assessment Using FT-ICR MS

Detection of the toxicity of a candidate compound at an early stage of drug development is an emerging area of interest. It is difficult to determine all of the effects of metabolism of a compound using traditional approaches such as histopathology and serum biochemistry. The goal of a metabolomics...

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Detalles Bibliográficos
Autores principales: Hasegawa, Mina, Ide, Mika, Kuwamura, Mitsuru, Yamate, Jyoji, Takenaka, Shigeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Toxicologic Pathology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234643/
https://www.ncbi.nlm.nih.gov/pubmed/22272014
http://dx.doi.org/10.1293/tox.23.67