Functional Properties of a Newly Identified C-terminal Splice Variant of Ca(v)1.3 L-type Ca(2+) Channels

An intramolecular interaction between a distal (DCRD) and a proximal regulatory domain (PCRD) within the C terminus of long Ca(v)1.3 L-type Ca(2+) channels (Ca(v)1.3(L)) is a major determinant of their voltage- and Ca(2+)-dependent gating kinetics. Removal of these regulatory domains by alternative...

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Detalles Bibliográficos
Autores principales: Bock, Gabriella, Gebhart, Mathias, Scharinger, Anja, Jangsangthong, Wanchana, Busquet, Perrine, Poggiani, Chiara, Sartori, Simone, Mangoni, Matteo E., Sinnegger-Brauns, Martina J., Herzig, Stefan, Striessnig, Jörg, Koschak, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234942/
https://www.ncbi.nlm.nih.gov/pubmed/21998310
http://dx.doi.org/10.1074/jbc.M111.269951

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