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Pharmacogenetic profiling and cetuximab outcome in patients with advanced colorectal cancer

BACKGROUND: We analyzed the influence of 8 germinal polymorphisms of candidate genes potentially related to EGFR signalling (EGFR, EGF, CCND1) or antibody-directed cell cytotoxicity (FCGR2A and FCGR3A) on outcome of colorectal cancer (CRC) patients receiving cetuximab-based therapy. METHODS: Fifty-e...

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Detalles Bibliográficos
Autores principales:	Dahan, Laetitia, Norguet, Emmanuelle, Etienne-Grimaldi, Marie-Christine, Formento, Jean-Louis, Gasmi, Mohamed, Nanni, Isabelle, Gaudart, Jean, Garcia, Stéphane, Ouafik, L'Houcine, Seitz, Jean-François, Milano, Gérard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235081/ https://www.ncbi.nlm.nih.gov/pubmed/22117530 http://dx.doi.org/10.1186/1471-2407-11-496

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