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Streamlining Homogeneous Glycoprotein Production for Biophysical and Structural Applications by Targeted Cell Line Development
Studying the biophysical characteristics of glycosylated proteins and solving their three-dimensional structures requires homogeneous recombinant protein of high quality.We introduce here a new approach to produce glycoproteins in homogenous form with the well-established, glycosylation mutant CHO L...
Autores principales: | Wilke, Sonja, Groebe, Lothar, Maffenbeier, Vitali, Jäger, Volker, Gossen, Manfred, Josewski, Jörn, Duda, Agathe, Polle, Lilia, Owens, Raymond J., Wirth, Dagmar, Heinz, Dirk W., van den Heuvel, Joop, Büssow, Konrad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235087/ https://www.ncbi.nlm.nih.gov/pubmed/22174749 http://dx.doi.org/10.1371/journal.pone.0027829 |
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