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Neutrophil Elastase Enhances Sputum Solubilization in Cystic Fibrosis Patients Receiving DNase Therapy

Cystic fibrosis patients suffer from chronic lung infection and inflammation due to the secretion of viscous sputum. Sputum viscosity is caused by extracellular DNA, some of which originates from the release of neutrophil extracellular traps (NETs). During NET formation neutrophil elastase (NE) part...

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Detalles Bibliográficos
Autores principales:	Papayannopoulos, Venizelos, Staab, Doris, Zychlinsky, Arturo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235130/ https://www.ncbi.nlm.nih.gov/pubmed/22174830 http://dx.doi.org/10.1371/journal.pone.0028526

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