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Combined 3D and hypoxic culture improves cartilage-specific gene expression in human chondrocytes
BACKGROUND AND PURPOSE: In vitro expansion of autologous chondrocytes is an essential part of many clinically used cartilage repair treatments. Native chondrocytes reside in a 3-dimensional (3D) network and are exposed to low levels of oxygen. We compared monolayer culture to combined 3D and hypoxic...
Autores principales: | Foldager, Casper B, Nielsen, Anna B, Munir, Samir, Ulrich-Vinther, Michael, Søballe, Kjeld, Bünger, Cody, Lind, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Informa Healthcare
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235297/ https://www.ncbi.nlm.nih.gov/pubmed/21434761 http://dx.doi.org/10.3109/17453674.2011.566135 |
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