Cargando…
Function of Membrane Rafts in Viral Lifecycles and Host Cellular Response
Membrane rafts are small (10–200 nm) sterol- and sphingolipid-enriched domains that compartmentalize cellular processes. Membrane rafts play an important role in viral infection cycles and viral virulence. Viruses are divided into four main classes, enveloped DNA virus, enveloped RNA virus, nonenvel...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235436/ https://www.ncbi.nlm.nih.gov/pubmed/22191032 http://dx.doi.org/10.1155/2011/245090 |
_version_ | 1782218599291682816 |
---|---|
author | Takahashi, Tadanobu Suzuki, Takashi |
author_facet | Takahashi, Tadanobu Suzuki, Takashi |
author_sort | Takahashi, Tadanobu |
collection | PubMed |
description | Membrane rafts are small (10–200 nm) sterol- and sphingolipid-enriched domains that compartmentalize cellular processes. Membrane rafts play an important role in viral infection cycles and viral virulence. Viruses are divided into four main classes, enveloped DNA virus, enveloped RNA virus, nonenveloped DNA virus, and nonenveloped RNA virus. General virus infection cycle is also classified into two sections, the early stage (entry process) and the late stage (assembly, budding, and release processes of virus particles). In the viral cycle, membrane rafts act as a scaffold of many cellular signal transductions, which are associated with symptoms caused by viral infections. In this paper, we describe the functions of membrane rafts in viral lifecycles and host cellular response according to each virus classification, each stage of the virus lifecycle, and each virus-induced signal transduction. |
format | Online Article Text |
id | pubmed-3235436 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-32354362011-12-21 Function of Membrane Rafts in Viral Lifecycles and Host Cellular Response Takahashi, Tadanobu Suzuki, Takashi Biochem Res Int Review Article Membrane rafts are small (10–200 nm) sterol- and sphingolipid-enriched domains that compartmentalize cellular processes. Membrane rafts play an important role in viral infection cycles and viral virulence. Viruses are divided into four main classes, enveloped DNA virus, enveloped RNA virus, nonenveloped DNA virus, and nonenveloped RNA virus. General virus infection cycle is also classified into two sections, the early stage (entry process) and the late stage (assembly, budding, and release processes of virus particles). In the viral cycle, membrane rafts act as a scaffold of many cellular signal transductions, which are associated with symptoms caused by viral infections. In this paper, we describe the functions of membrane rafts in viral lifecycles and host cellular response according to each virus classification, each stage of the virus lifecycle, and each virus-induced signal transduction. Hindawi Publishing Corporation 2011 2011-12-07 /pmc/articles/PMC3235436/ /pubmed/22191032 http://dx.doi.org/10.1155/2011/245090 Text en Copyright © 2011 T. Takahashi and T. Suzuki. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Takahashi, Tadanobu Suzuki, Takashi Function of Membrane Rafts in Viral Lifecycles and Host Cellular Response |
title | Function of Membrane Rafts in Viral Lifecycles and Host Cellular Response |
title_full | Function of Membrane Rafts in Viral Lifecycles and Host Cellular Response |
title_fullStr | Function of Membrane Rafts in Viral Lifecycles and Host Cellular Response |
title_full_unstemmed | Function of Membrane Rafts in Viral Lifecycles and Host Cellular Response |
title_short | Function of Membrane Rafts in Viral Lifecycles and Host Cellular Response |
title_sort | function of membrane rafts in viral lifecycles and host cellular response |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235436/ https://www.ncbi.nlm.nih.gov/pubmed/22191032 http://dx.doi.org/10.1155/2011/245090 |
work_keys_str_mv | AT takahashitadanobu functionofmembraneraftsinvirallifecyclesandhostcellularresponse AT suzukitakashi functionofmembraneraftsinvirallifecyclesandhostcellularresponse |