Cargando…

When Cells Suffocate: Autophagy in Cancer and Immune Cells under Low Oxygen

Hypoxia is a signature feature of growing tumors. This cellular state creates an inhospitable condition that impedes the growth and function of all cells within the immediate and surrounding tumor microenvironment. To adapt to hypoxia, cells activate autophagy and undergo a metabolic shift increasin...

Descripción completa

Detalles Bibliográficos
Autores principales: Schlie, Katrin, Spowart, Jaeline E., Hughson, Luke R. K., Townsend, Katelin N., Lum, Julian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235465/
https://www.ncbi.nlm.nih.gov/pubmed/22190938
http://dx.doi.org/10.1155/2011/470597