A long-term siRNA strategy regulates fibronectin overexpression and improves vascular lesions in retinas of diabetic rats

PURPOSE: A sustained gene modulatory strategy is necessary for regulating abnormal gene expression in diabetic retinopathy, a long-term complication. We investigated the efficacy of a small interference RNA (siRNA) strategy in mediating the long-term downregulatory effect of fibronectin (FN) overexp...

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Detalles Bibliográficos
Autores principales: Roy, Sumon, Nasser, Sigrid, Yee, Melissa, Graves, Dana T., Roy, Sayon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235535/
https://www.ncbi.nlm.nih.gov/pubmed/22171163

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