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NF-κB feedback control of JNK1 activation modulates TRPV1-induced increases in IL-6 and IL-8 release by human corneal epithelial cells
PURPOSE: The corneal wound healing response to an alkali burn results in dysregulated inflammation and opacity. Transient receptor potential vanilloid type1 (TRPV1) ion channel activation by such a stress contributes to this unfavorable outcome. Accordingly, we sought to identify potential drug targ...
Autores principales: | Wang, Z., Yang, Y., Yang, H., Capó-Aponte, J.E., Tachado, S.D., Wolosin, J.M., Reinach, P.S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235537/ https://www.ncbi.nlm.nih.gov/pubmed/22171160 |
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