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Diabetic Nephropathy Amelioration by a Low-Dose Sitagliptin in an Animal Model of Type 2 Diabetes (Zucker Diabetic Fatty Rat)
This study was performed to assess the effect of chronic low-dose sitagliptin, a dipeptidyl peptidase 4 inhibitor, on metabolic profile and on renal lesions aggravation in a rat model of type-2 diabetic nephropathy, the Zucker diabetic fatty (ZDF) rat. Diabetic and obese ZDF (fa/fa) rats and their c...
Autores principales: | Mega, Cristina, Teixeira de Lemos, Edite, Vala, Helena, Fernandes, Rosa, Oliveira, Jorge, Mascarenhas-Melo, Filipa, Teixeira, Frederico, Reis, Flávio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235777/ https://www.ncbi.nlm.nih.gov/pubmed/22203828 http://dx.doi.org/10.1155/2011/162092 |
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