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Diabetic Nephropathy Amelioration by a Low-Dose Sitagliptin in an Animal Model of Type 2 Diabetes (Zucker Diabetic Fatty Rat)

This study was performed to assess the effect of chronic low-dose sitagliptin, a dipeptidyl peptidase 4 inhibitor, on metabolic profile and on renal lesions aggravation in a rat model of type-2 diabetic nephropathy, the Zucker diabetic fatty (ZDF) rat. Diabetic and obese ZDF (fa/fa) rats and their c...

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Detalles Bibliográficos
Autores principales: Mega, Cristina, Teixeira de Lemos, Edite, Vala, Helena, Fernandes, Rosa, Oliveira, Jorge, Mascarenhas-Melo, Filipa, Teixeira, Frederico, Reis, Flávio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235777/
https://www.ncbi.nlm.nih.gov/pubmed/22203828
http://dx.doi.org/10.1155/2011/162092

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