Preeclampsia, Hypoxia, Thrombosis, and Inflammation

Reductions in uteroplacental flow initiate a cascade of molecular effects leading to hypoxia, thrombosis, inflammation, and endothelial cell dysfunction resulting in untoward pregnancy outcomes. In this review, we detail these effects and their relationship to preeclampsia (PE) and intrauterine grow...

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Detalles Bibliográficos
Autores principales: Shamshirsaz, Amir A., Paidas, Michael, Krikun, Graciela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235807/
https://www.ncbi.nlm.nih.gov/pubmed/22175023
http://dx.doi.org/10.1155/2012/374047
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author Shamshirsaz, Amir A.
Paidas, Michael
Krikun, Graciela
author_facet Shamshirsaz, Amir A.
Paidas, Michael
Krikun, Graciela
author_sort Shamshirsaz, Amir A.
collection PubMed
description Reductions in uteroplacental flow initiate a cascade of molecular effects leading to hypoxia, thrombosis, inflammation, and endothelial cell dysfunction resulting in untoward pregnancy outcomes. In this review, we detail these effects and their relationship to preeclampsia (PE) and intrauterine growth restriction (IUGR).
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spelling pubmed-32358072011-12-15 Preeclampsia, Hypoxia, Thrombosis, and Inflammation Shamshirsaz, Amir A. Paidas, Michael Krikun, Graciela J Pregnancy Review Article Reductions in uteroplacental flow initiate a cascade of molecular effects leading to hypoxia, thrombosis, inflammation, and endothelial cell dysfunction resulting in untoward pregnancy outcomes. In this review, we detail these effects and their relationship to preeclampsia (PE) and intrauterine growth restriction (IUGR). Hindawi Publishing Corporation 2012 2011-12-11 /pmc/articles/PMC3235807/ /pubmed/22175023 http://dx.doi.org/10.1155/2012/374047 Text en Copyright © 2012 Amir A. Shamshirsaz et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Shamshirsaz, Amir A.
Paidas, Michael
Krikun, Graciela
Preeclampsia, Hypoxia, Thrombosis, and Inflammation
title Preeclampsia, Hypoxia, Thrombosis, and Inflammation
title_full Preeclampsia, Hypoxia, Thrombosis, and Inflammation
title_fullStr Preeclampsia, Hypoxia, Thrombosis, and Inflammation
title_full_unstemmed Preeclampsia, Hypoxia, Thrombosis, and Inflammation
title_short Preeclampsia, Hypoxia, Thrombosis, and Inflammation
title_sort preeclampsia, hypoxia, thrombosis, and inflammation
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235807/
https://www.ncbi.nlm.nih.gov/pubmed/22175023
http://dx.doi.org/10.1155/2012/374047
work_keys_str_mv AT shamshirsazamira preeclampsiahypoxiathrombosisandinflammation
AT paidasmichael preeclampsiahypoxiathrombosisandinflammation
AT krikungraciela preeclampsiahypoxiathrombosisandinflammation

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