Cargando…

Prevention of Vascular Dysfunction after Preeclampsia: A Potential Long-Term Outcome Measure and an Emerging Goal for Treatment

Preeclampsia is increasingly being recognised as more than an isolated disease of pregnancy. In particular, preeclampsia has emerged as an independent risk factor for maternal cardiovascular disease and has recently been recognised as a risk factor for cardiovascular disease in children exposed in u...

Descripción completa

Detalles Bibliográficos
Autores principales: Lazdam, Merzaka, Davis, Esther F., Lewandowski, Adam J., Worton, Stephanie A., Kenworthy, Yvonne, Kelly, Brenda, Leeson, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235810/
https://www.ncbi.nlm.nih.gov/pubmed/22175025
http://dx.doi.org/10.1155/2012/704146
_version_ 1782218638170783744
author Lazdam, Merzaka
Davis, Esther F.
Lewandowski, Adam J.
Worton, Stephanie A.
Kenworthy, Yvonne
Kelly, Brenda
Leeson, Paul
author_facet Lazdam, Merzaka
Davis, Esther F.
Lewandowski, Adam J.
Worton, Stephanie A.
Kenworthy, Yvonne
Kelly, Brenda
Leeson, Paul
author_sort Lazdam, Merzaka
collection PubMed
description Preeclampsia is increasingly being recognised as more than an isolated disease of pregnancy. In particular, preeclampsia has emerged as an independent risk factor for maternal cardiovascular disease and has recently been recognised as a risk factor for cardiovascular disease in children exposed in utero. Preeclampsia and cardiovascular disease may share important pathophysiological and molecular mechanisms and further investigation into these is likely to offer insight into the origins of both conditions. This paper considers the links between cardiovascular disease and preeclampsia and the implication of these findings for refinement of the management of patients whose care is complicated by preeclampsia.
format Online
Article
Text
id pubmed-3235810
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-32358102011-12-15 Prevention of Vascular Dysfunction after Preeclampsia: A Potential Long-Term Outcome Measure and an Emerging Goal for Treatment Lazdam, Merzaka Davis, Esther F. Lewandowski, Adam J. Worton, Stephanie A. Kenworthy, Yvonne Kelly, Brenda Leeson, Paul J Pregnancy Review Article Preeclampsia is increasingly being recognised as more than an isolated disease of pregnancy. In particular, preeclampsia has emerged as an independent risk factor for maternal cardiovascular disease and has recently been recognised as a risk factor for cardiovascular disease in children exposed in utero. Preeclampsia and cardiovascular disease may share important pathophysiological and molecular mechanisms and further investigation into these is likely to offer insight into the origins of both conditions. This paper considers the links between cardiovascular disease and preeclampsia and the implication of these findings for refinement of the management of patients whose care is complicated by preeclampsia. Hindawi Publishing Corporation 2012 2011-12-08 /pmc/articles/PMC3235810/ /pubmed/22175025 http://dx.doi.org/10.1155/2012/704146 Text en Copyright © 2012 Merzaka Lazdam et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Lazdam, Merzaka
Davis, Esther F.
Lewandowski, Adam J.
Worton, Stephanie A.
Kenworthy, Yvonne
Kelly, Brenda
Leeson, Paul
Prevention of Vascular Dysfunction after Preeclampsia: A Potential Long-Term Outcome Measure and an Emerging Goal for Treatment
title Prevention of Vascular Dysfunction after Preeclampsia: A Potential Long-Term Outcome Measure and an Emerging Goal for Treatment
title_full Prevention of Vascular Dysfunction after Preeclampsia: A Potential Long-Term Outcome Measure and an Emerging Goal for Treatment
title_fullStr Prevention of Vascular Dysfunction after Preeclampsia: A Potential Long-Term Outcome Measure and an Emerging Goal for Treatment
title_full_unstemmed Prevention of Vascular Dysfunction after Preeclampsia: A Potential Long-Term Outcome Measure and an Emerging Goal for Treatment
title_short Prevention of Vascular Dysfunction after Preeclampsia: A Potential Long-Term Outcome Measure and an Emerging Goal for Treatment
title_sort prevention of vascular dysfunction after preeclampsia: a potential long-term outcome measure and an emerging goal for treatment
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235810/
https://www.ncbi.nlm.nih.gov/pubmed/22175025
http://dx.doi.org/10.1155/2012/704146
work_keys_str_mv AT lazdammerzaka preventionofvasculardysfunctionafterpreeclampsiaapotentiallongtermoutcomemeasureandanemerginggoalfortreatment
AT davisestherf preventionofvasculardysfunctionafterpreeclampsiaapotentiallongtermoutcomemeasureandanemerginggoalfortreatment
AT lewandowskiadamj preventionofvasculardysfunctionafterpreeclampsiaapotentiallongtermoutcomemeasureandanemerginggoalfortreatment
AT wortonstephaniea preventionofvasculardysfunctionafterpreeclampsiaapotentiallongtermoutcomemeasureandanemerginggoalfortreatment
AT kenworthyyvonne preventionofvasculardysfunctionafterpreeclampsiaapotentiallongtermoutcomemeasureandanemerginggoalfortreatment
AT kellybrenda preventionofvasculardysfunctionafterpreeclampsiaapotentiallongtermoutcomemeasureandanemerginggoalfortreatment
AT leesonpaul preventionofvasculardysfunctionafterpreeclampsiaapotentiallongtermoutcomemeasureandanemerginggoalfortreatment