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ABO Incompatible Kidney Transplantation—Current Status and Uncertainties

In the past, ABO blood group incompatibility was considered an absolute contraindication for kidney transplantation. Progress in defined desensitization practice and immunologic understanding has allowed increasingly successful ABO incompatible transplantation during recent years. This paper focused...

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Detalles Bibliográficos
Autores principales: Shin, Milljae, Kim, Sung-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235893/
https://www.ncbi.nlm.nih.gov/pubmed/22174989
http://dx.doi.org/10.1155/2011/970421
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author Shin, Milljae
Kim, Sung-Joo
author_facet Shin, Milljae
Kim, Sung-Joo
author_sort Shin, Milljae
collection PubMed
description In the past, ABO blood group incompatibility was considered an absolute contraindication for kidney transplantation. Progress in defined desensitization practice and immunologic understanding has allowed increasingly successful ABO incompatible transplantation during recent years. This paper focused on the history, disserted outcomes, desensitization modalities and protocols, posttransplant immunologic surveillance, and antibody-mediated rejection in transplantation with an ABO incompatible kidney allograft. The mechanism underlying accommodation and antibody-mediated injury was also described.
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spelling pubmed-32358932011-12-15 ABO Incompatible Kidney Transplantation—Current Status and Uncertainties Shin, Milljae Kim, Sung-Joo J Transplant Review Article In the past, ABO blood group incompatibility was considered an absolute contraindication for kidney transplantation. Progress in defined desensitization practice and immunologic understanding has allowed increasingly successful ABO incompatible transplantation during recent years. This paper focused on the history, disserted outcomes, desensitization modalities and protocols, posttransplant immunologic surveillance, and antibody-mediated rejection in transplantation with an ABO incompatible kidney allograft. The mechanism underlying accommodation and antibody-mediated injury was also described. Hindawi Publishing Corporation 2011 2011-12-10 /pmc/articles/PMC3235893/ /pubmed/22174989 http://dx.doi.org/10.1155/2011/970421 Text en Copyright © 2011 M. Shin and S.-J. Kim. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Shin, Milljae
Kim, Sung-Joo
ABO Incompatible Kidney Transplantation—Current Status and Uncertainties
title ABO Incompatible Kidney Transplantation—Current Status and Uncertainties
title_full ABO Incompatible Kidney Transplantation—Current Status and Uncertainties
title_fullStr ABO Incompatible Kidney Transplantation—Current Status and Uncertainties
title_full_unstemmed ABO Incompatible Kidney Transplantation—Current Status and Uncertainties
title_short ABO Incompatible Kidney Transplantation—Current Status and Uncertainties
title_sort abo incompatible kidney transplantation—current status and uncertainties
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235893/
https://www.ncbi.nlm.nih.gov/pubmed/22174989
http://dx.doi.org/10.1155/2011/970421
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