Synthesis of Rhodamines from Fluoresceins Using Pd-Catalyzed C–N Cross-Coupling

[Image: see text] A unified, convenient, and efficient strategy for the preparation of rhodamines and N,N′-diacylated rhodamines has been developed. Fluorescein ditriflates were found to undergo palladium-catalyzed C–N cross-coupling with amines, amides, carbamates, and other nitrogen nucleophiles t...

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Autores principales: Grimm, Jonathan B., Lavis, Luke D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235915/
https://www.ncbi.nlm.nih.gov/pubmed/22091952
http://dx.doi.org/10.1021/ol202618t
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author Grimm, Jonathan B.
Lavis, Luke D.
author_facet Grimm, Jonathan B.
Lavis, Luke D.
author_sort Grimm, Jonathan B.
collection PubMed
description [Image: see text] A unified, convenient, and efficient strategy for the preparation of rhodamines and N,N′-diacylated rhodamines has been developed. Fluorescein ditriflates were found to undergo palladium-catalyzed C–N cross-coupling with amines, amides, carbamates, and other nitrogen nucleophiles to provide direct access to known and novel rhodamine derivatives, including fluorescent dyes, quenchers, and latent fluorophores.
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spelling pubmed-32359152011-12-12 Synthesis of Rhodamines from Fluoresceins Using Pd-Catalyzed C–N Cross-Coupling Grimm, Jonathan B. Lavis, Luke D. Org Lett [Image: see text] A unified, convenient, and efficient strategy for the preparation of rhodamines and N,N′-diacylated rhodamines has been developed. Fluorescein ditriflates were found to undergo palladium-catalyzed C–N cross-coupling with amines, amides, carbamates, and other nitrogen nucleophiles to provide direct access to known and novel rhodamine derivatives, including fluorescent dyes, quenchers, and latent fluorophores. American Chemical Society 2011-11-17 2011-12-16 /pmc/articles/PMC3235915/ /pubmed/22091952 http://dx.doi.org/10.1021/ol202618t Text en Copyright © 2011 American Chemical Society http://pubs.acs.org This is an open-access article distributed under the ACS AuthorChoice Terms & Conditions. Any use of this article, must conform to the terms of that license which are available at http://pubs.acs.org.
spellingShingle Grimm, Jonathan B.
Lavis, Luke D.
Synthesis of Rhodamines from Fluoresceins Using Pd-Catalyzed C–N Cross-Coupling
title Synthesis of Rhodamines from Fluoresceins Using Pd-Catalyzed C–N Cross-Coupling
title_full Synthesis of Rhodamines from Fluoresceins Using Pd-Catalyzed C–N Cross-Coupling
title_fullStr Synthesis of Rhodamines from Fluoresceins Using Pd-Catalyzed C–N Cross-Coupling
title_full_unstemmed Synthesis of Rhodamines from Fluoresceins Using Pd-Catalyzed C–N Cross-Coupling
title_short Synthesis of Rhodamines from Fluoresceins Using Pd-Catalyzed C–N Cross-Coupling
title_sort synthesis of rhodamines from fluoresceins using pd-catalyzed c–n cross-coupling
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235915/
https://www.ncbi.nlm.nih.gov/pubmed/22091952
http://dx.doi.org/10.1021/ol202618t
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