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Lipofuscin Hypothesis of Alzheimer's Disease
The primary culprit responsible for Alzheimer's disease (AD) remains unknown. Aβ protein has been identified as the main component of amyloid of senile plaques, the hallmark lesion of AD, but it is not definitively established whether the formation of extracellular Aβ deposits is the absolute h...
Autores principales: | Giaccone, Giorgio, Orsi, Laura, Cupidi, Chiara, Tagliavini, Fabrizio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235942/ https://www.ncbi.nlm.nih.gov/pubmed/22545040 http://dx.doi.org/10.1159/000329544 |
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