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Oral ezatiostat HCl (Telintra(®), TLK199) and Idiopathic Chronic Neutropenia (ICN): a case report of complete response of a patient with G-CSF resistant ICN following treatment with ezatiostat, a glutathione S-transferase P1-1 (GSTP1-1) inhibitor
Idiopathic chronic neutropenia (ICN) describes a heterogeneous group of hematologic diseases characterized by low circulating neutrophil levels often associated with recurrent fevers, chronic mucosal inflammation, and severe systemic infections. The severity and risk of complications, including seri...
Autores principales: | Lyons, Roger M, Wilks, Sharon T, Young, Shelby, Brown, Gail L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235963/ https://www.ncbi.nlm.nih.gov/pubmed/22047626 http://dx.doi.org/10.1186/1756-8722-4-43 |
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