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Imatinib Mesylate: Past Successes and Future Challenges in the Treatment of Gastrointestinal Stromal Tumors
Just over a decade ago, gastrointestinal tumours were a poorly understood mesenchymal neoplasm unsuccessfully treated with chemotherapy. Cytotoxic therapy for advanced disease yielded response rates of 10% and median survival of just 18 months. However, the discovery of KIT and platelet derived grow...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Libertas Academica
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235999/ https://www.ncbi.nlm.nih.gov/pubmed/22174597 http://dx.doi.org/10.4137/CMO.S4259 |