Paroxysmal Nocturnal Hemoglobinuria Presenting with a Left Intraventricular Thrombus in a Patient with Prior Thymoma and Aplastic Anemia

We report the case of a 37-year old man presenting with a left ventricular cardiac thrombus in the setting of subclinical paroxysmal nocturnal hemoglobinura (PNH) developing two years after immunosuppressive therapy for thymoma-associated aplastic anemia. The literature regarding the interplay betwe...

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Detalles Bibliográficos
Autores principales: Migdady, Yazan, Olszewski, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236000/
https://www.ncbi.nlm.nih.gov/pubmed/22174595
http://dx.doi.org/10.4137/CMO.S8442
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author Migdady, Yazan
Olszewski, Adam J.
author_facet Migdady, Yazan
Olszewski, Adam J.
author_sort Migdady, Yazan
collection PubMed
description We report the case of a 37-year old man presenting with a left ventricular cardiac thrombus in the setting of subclinical paroxysmal nocturnal hemoglobinura (PNH) developing two years after immunosuppressive therapy for thymoma-associated aplastic anemia. The literature regarding the interplay between autoimmunity and immunosuppression, aplastic anemia, thymoma and the emergence of PNH is reviewed.
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spelling pubmed-32360002011-12-15 Paroxysmal Nocturnal Hemoglobinuria Presenting with a Left Intraventricular Thrombus in a Patient with Prior Thymoma and Aplastic Anemia Migdady, Yazan Olszewski, Adam J. Clin Med Insights Oncol Case Report We report the case of a 37-year old man presenting with a left ventricular cardiac thrombus in the setting of subclinical paroxysmal nocturnal hemoglobinura (PNH) developing two years after immunosuppressive therapy for thymoma-associated aplastic anemia. The literature regarding the interplay between autoimmunity and immunosuppression, aplastic anemia, thymoma and the emergence of PNH is reviewed. Libertas Academica 2011-11-03 /pmc/articles/PMC3236000/ /pubmed/22174595 http://dx.doi.org/10.4137/CMO.S8442 Text en © the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article. Unrestricted non-commercial use is permitted provided the original work is properly cited.
spellingShingle Case Report
Migdady, Yazan
Olszewski, Adam J.
Paroxysmal Nocturnal Hemoglobinuria Presenting with a Left Intraventricular Thrombus in a Patient with Prior Thymoma and Aplastic Anemia
title Paroxysmal Nocturnal Hemoglobinuria Presenting with a Left Intraventricular Thrombus in a Patient with Prior Thymoma and Aplastic Anemia
title_full Paroxysmal Nocturnal Hemoglobinuria Presenting with a Left Intraventricular Thrombus in a Patient with Prior Thymoma and Aplastic Anemia
title_fullStr Paroxysmal Nocturnal Hemoglobinuria Presenting with a Left Intraventricular Thrombus in a Patient with Prior Thymoma and Aplastic Anemia
title_full_unstemmed Paroxysmal Nocturnal Hemoglobinuria Presenting with a Left Intraventricular Thrombus in a Patient with Prior Thymoma and Aplastic Anemia
title_short Paroxysmal Nocturnal Hemoglobinuria Presenting with a Left Intraventricular Thrombus in a Patient with Prior Thymoma and Aplastic Anemia
title_sort paroxysmal nocturnal hemoglobinuria presenting with a left intraventricular thrombus in a patient with prior thymoma and aplastic anemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236000/
https://www.ncbi.nlm.nih.gov/pubmed/22174595
http://dx.doi.org/10.4137/CMO.S8442
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AT olszewskiadamj paroxysmalnocturnalhemoglobinuriapresentingwithaleftintraventricularthrombusinapatientwithpriorthymomaandaplasticanemia

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