Drug Rash with Eosinophilia and Systemic Symptoms: Two Emergency Department Cases

Drug rash with eosinophilia and systemic symptoms (DRESS) is a rare, severe adverse drug event that appears with a generalized rash, fevers, and dysfunction of 1 or more organ systems. We describe 2 patients (1 adult and 1 pediatric) seen in the emergency department with DRESS, and review the clinic...

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Detalles Bibliográficos
Autores principales: Tsyrulnik, Alina, Landman, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Department of Emergency Medicine, University of California, Irvine 2011
Materias:
Dermatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236166/
https://www.ncbi.nlm.nih.gov/pubmed/22224160
http://dx.doi.org/10.5811/westjem.2010.11.2077
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author Tsyrulnik, Alina
Landman, Adam
author_facet Tsyrulnik, Alina
Landman, Adam
author_sort Tsyrulnik, Alina
collection PubMed
description Drug rash with eosinophilia and systemic symptoms (DRESS) is a rare, severe adverse drug event that appears with a generalized rash, fevers, and dysfunction of 1 or more organ systems. We describe 2 patients (1 adult and 1 pediatric) seen in the emergency department with DRESS, and review the clinical presentations, potential complications, and management of DRESS. Although rare, it can be associated with significant morbidity, including liver failure and death, and should be considered in the differential diagnosis of patients with diffuse rash and systemic symptoms.
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spelling pubmed-32361662012-01-05 Drug Rash with Eosinophilia and Systemic Symptoms: Two Emergency Department Cases Tsyrulnik, Alina Landman, Adam West J Emerg Med Dermatology Drug rash with eosinophilia and systemic symptoms (DRESS) is a rare, severe adverse drug event that appears with a generalized rash, fevers, and dysfunction of 1 or more organ systems. We describe 2 patients (1 adult and 1 pediatric) seen in the emergency department with DRESS, and review the clinical presentations, potential complications, and management of DRESS. Although rare, it can be associated with significant morbidity, including liver failure and death, and should be considered in the differential diagnosis of patients with diffuse rash and systemic symptoms. Department of Emergency Medicine, University of California, Irvine 2011-11 /pmc/articles/PMC3236166/ /pubmed/22224160 http://dx.doi.org/10.5811/westjem.2010.11.2077 Text en the authors http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) License. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Dermatology
Tsyrulnik, Alina
Landman, Adam
Drug Rash with Eosinophilia and Systemic Symptoms: Two Emergency Department Cases
title Drug Rash with Eosinophilia and Systemic Symptoms: Two Emergency Department Cases
title_full Drug Rash with Eosinophilia and Systemic Symptoms: Two Emergency Department Cases
title_fullStr Drug Rash with Eosinophilia and Systemic Symptoms: Two Emergency Department Cases
title_full_unstemmed Drug Rash with Eosinophilia and Systemic Symptoms: Two Emergency Department Cases
title_short Drug Rash with Eosinophilia and Systemic Symptoms: Two Emergency Department Cases
title_sort drug rash with eosinophilia and systemic symptoms: two emergency department cases
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236166/
https://www.ncbi.nlm.nih.gov/pubmed/22224160
http://dx.doi.org/10.5811/westjem.2010.11.2077
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