XPA-Mediated Regulation of Global Nucleotide Excision Repair by ATR Is p53-Dependent and Occurs Primarily in S-Phase

Cell cycle checkpoints play an important role in regulation of DNA repair pathways. However, how the regulation occurs throughout the cell cycle remains largely unknown. Here we demonstrate that nucleotide excision repair (NER) is regulated by the ATR/p53 checkpoint via modulation of XPA nuclear imp...

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Detalles Bibliográficos
Autores principales: Li, Zhengke, Musich, Phillip R., Serrano, Moises A., Dong, Zhiping, Zou, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236200/
https://www.ncbi.nlm.nih.gov/pubmed/22174788
http://dx.doi.org/10.1371/journal.pone.0028326

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