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A Novel N-Acetylglutamate Synthase Architecture Revealed by the Crystal Structure of the Bifunctional Enzyme from Maricaulis maris

Novel bifunctional N-acetylglutamate synthase/kinases (NAGS/K) that catalyze the first two steps of arginine biosynthesis and are homologous to vertebrate N-acetylglutamate synthase (NAGS), an essential cofactor-producing enzyme in the urea cycle, were identified in Maricaulis maris and several othe...

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Detalles Bibliográficos
Autores principales: Shi, Dashuang, Li, Yongdong, Cabrera-Luque, Juan, Jin, Zhongmin, Yu, Xiaolin, Zhao, Gengxiang, Haskins, Nantaporn, Allewell, Norma M., Tuchman, Mendel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236213/
https://www.ncbi.nlm.nih.gov/pubmed/22174908
http://dx.doi.org/10.1371/journal.pone.0028825