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A Novel N-Acetylglutamate Synthase Architecture Revealed by the Crystal Structure of the Bifunctional Enzyme from Maricaulis maris
Novel bifunctional N-acetylglutamate synthase/kinases (NAGS/K) that catalyze the first two steps of arginine biosynthesis and are homologous to vertebrate N-acetylglutamate synthase (NAGS), an essential cofactor-producing enzyme in the urea cycle, were identified in Maricaulis maris and several othe...
Autores principales: | Shi, Dashuang, Li, Yongdong, Cabrera-Luque, Juan, Jin, Zhongmin, Yu, Xiaolin, Zhao, Gengxiang, Haskins, Nantaporn, Allewell, Norma M., Tuchman, Mendel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236213/ https://www.ncbi.nlm.nih.gov/pubmed/22174908 http://dx.doi.org/10.1371/journal.pone.0028825 |
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