Cargando…

The Effect of Arrestin Conformation on the Recruitment of c-Raf1, MEK1, and ERK1/2 Activation

Arrestins are multifunctional signaling adaptors originally discovered as proteins that “arrest” G protein activation by G protein-coupled receptors (GPCRs). Recently GPCR complexes with arrestins have been proposed to activate G protein-independent signaling pathways. In particular, arrestin-depend...

Descripción completa

Detalles Bibliográficos
Autores principales: Coffa, Sergio, Breitman, Maya, Hanson, Susan M., Callaway, Kari, Kook, Seunghyi, Dalby, Kevin N., Gurevich, Vsevolod V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236217/
https://www.ncbi.nlm.nih.gov/pubmed/22174878
http://dx.doi.org/10.1371/journal.pone.0028723