Cargando…
The Effect of Arrestin Conformation on the Recruitment of c-Raf1, MEK1, and ERK1/2 Activation
Arrestins are multifunctional signaling adaptors originally discovered as proteins that “arrest” G protein activation by G protein-coupled receptors (GPCRs). Recently GPCR complexes with arrestins have been proposed to activate G protein-independent signaling pathways. In particular, arrestin-depend...
Autores principales: | Coffa, Sergio, Breitman, Maya, Hanson, Susan M., Callaway, Kari, Kook, Seunghyi, Dalby, Kevin N., Gurevich, Vsevolod V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236217/ https://www.ncbi.nlm.nih.gov/pubmed/22174878 http://dx.doi.org/10.1371/journal.pone.0028723 |
Ejemplares similares
-
Arrestins regulate cell spreading and motility via focal adhesion dynamics
por: Cleghorn, Whitney M., et al.
Publicado: (2015) -
“RAF” neighborhood: Protein–protein interaction in the Raf/Mek/Erk pathway
por: Cseh, Botond, et al.
Publicado: (2014) -
Growth Inhibitory Signaling of the Raf/MEK/ERK Pathway
por: Wu, Pui-Kei, et al.
Publicado: (2020) -
Phosphorylation of β-arrestin2 at Thr(383) by MEK underlies β-arrestin-dependent activation of Erk1/2 by GPCRs
por: Cassier, Elisabeth, et al.
Publicado: (2017) -
RDM1 promotes neuroblastoma growth through the RAS–Raf–MEK–ERK pathway
por: Xie, Guojin, et al.
Publicado: (2019)