Cargando…

The Effects of a Multiflavonoid Supplement on Vascular and Hemodynamic Parameters following Acute Exercise

Antioxidants can decrease oxidative stress and combined with acute exercise they may lead to further decreases in blood pressure. The purpose of this study was to investigate the effects of 2 weeks of antioxidant supplementation on vascular distensibility and cardiovascular hemodynamics during poste...

Descripción completa

Detalles Bibliográficos
Autores principales: Kappus, Rebecca M., Curry, Chelsea D., McAnulty, Steve, Welsh, Janice, Morris, David, Nieman, David C., Soukup, Jeffrey, Collier, Scott R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236420/
https://www.ncbi.nlm.nih.gov/pubmed/22191012
http://dx.doi.org/10.1155/2011/210798
_version_ 1782218740727808000
author Kappus, Rebecca M.
Curry, Chelsea D.
McAnulty, Steve
Welsh, Janice
Morris, David
Nieman, David C.
Soukup, Jeffrey
Collier, Scott R.
author_facet Kappus, Rebecca M.
Curry, Chelsea D.
McAnulty, Steve
Welsh, Janice
Morris, David
Nieman, David C.
Soukup, Jeffrey
Collier, Scott R.
author_sort Kappus, Rebecca M.
collection PubMed
description Antioxidants can decrease oxidative stress and combined with acute exercise they may lead to further decreases in blood pressure. The purpose of this study was to investigate the effects of 2 weeks of antioxidant supplementation on vascular distensibility and cardiovascular hemodynamics during postexercise hypotension. Methods. Twenty young subjects were randomized to placebo (n = 10) or antioxidant supplementation (n = 10) for two weeks. Antioxidant status, vascular distensibility, and hemodynamics were obtained before, immediately, and 30 minutes after an acute bout of aerobic exercise both before and after supplementation. Results. Two weeks of antioxidant supplementation resulted in a greater systolic blood pressure (SBP) decrease during postexercise hypotension (PEH) and significant decreases in augmentation index versus placebo (12.5% versus 3.5%, resp.). Also ferric-reducing ability of plasma (FRAP) increased significantly (interaction P = 0.024) after supplementation. Conclusion. Supplementation showed an additive effect on PEH associated with increased FRAP values and decreases in systolic blood pressure and augmentation index.
format Online
Article
Text
id pubmed-3236420
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-32364202011-12-21 The Effects of a Multiflavonoid Supplement on Vascular and Hemodynamic Parameters following Acute Exercise Kappus, Rebecca M. Curry, Chelsea D. McAnulty, Steve Welsh, Janice Morris, David Nieman, David C. Soukup, Jeffrey Collier, Scott R. Oxid Med Cell Longev Research Article Antioxidants can decrease oxidative stress and combined with acute exercise they may lead to further decreases in blood pressure. The purpose of this study was to investigate the effects of 2 weeks of antioxidant supplementation on vascular distensibility and cardiovascular hemodynamics during postexercise hypotension. Methods. Twenty young subjects were randomized to placebo (n = 10) or antioxidant supplementation (n = 10) for two weeks. Antioxidant status, vascular distensibility, and hemodynamics were obtained before, immediately, and 30 minutes after an acute bout of aerobic exercise both before and after supplementation. Results. Two weeks of antioxidant supplementation resulted in a greater systolic blood pressure (SBP) decrease during postexercise hypotension (PEH) and significant decreases in augmentation index versus placebo (12.5% versus 3.5%, resp.). Also ferric-reducing ability of plasma (FRAP) increased significantly (interaction P = 0.024) after supplementation. Conclusion. Supplementation showed an additive effect on PEH associated with increased FRAP values and decreases in systolic blood pressure and augmentation index. Hindawi Publishing Corporation 2011 2011-12-04 /pmc/articles/PMC3236420/ /pubmed/22191012 http://dx.doi.org/10.1155/2011/210798 Text en Copyright © 2011 Rebecca M. Kappus et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Kappus, Rebecca M.
Curry, Chelsea D.
McAnulty, Steve
Welsh, Janice
Morris, David
Nieman, David C.
Soukup, Jeffrey
Collier, Scott R.
The Effects of a Multiflavonoid Supplement on Vascular and Hemodynamic Parameters following Acute Exercise
title The Effects of a Multiflavonoid Supplement on Vascular and Hemodynamic Parameters following Acute Exercise
title_full The Effects of a Multiflavonoid Supplement on Vascular and Hemodynamic Parameters following Acute Exercise
title_fullStr The Effects of a Multiflavonoid Supplement on Vascular and Hemodynamic Parameters following Acute Exercise
title_full_unstemmed The Effects of a Multiflavonoid Supplement on Vascular and Hemodynamic Parameters following Acute Exercise
title_short The Effects of a Multiflavonoid Supplement on Vascular and Hemodynamic Parameters following Acute Exercise
title_sort effects of a multiflavonoid supplement on vascular and hemodynamic parameters following acute exercise
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236420/
https://www.ncbi.nlm.nih.gov/pubmed/22191012
http://dx.doi.org/10.1155/2011/210798
work_keys_str_mv AT kappusrebeccam theeffectsofamultiflavonoidsupplementonvascularandhemodynamicparametersfollowingacuteexercise
AT currychelsead theeffectsofamultiflavonoidsupplementonvascularandhemodynamicparametersfollowingacuteexercise
AT mcanultysteve theeffectsofamultiflavonoidsupplementonvascularandhemodynamicparametersfollowingacuteexercise
AT welshjanice theeffectsofamultiflavonoidsupplementonvascularandhemodynamicparametersfollowingacuteexercise
AT morrisdavid theeffectsofamultiflavonoidsupplementonvascularandhemodynamicparametersfollowingacuteexercise
AT niemandavidc theeffectsofamultiflavonoidsupplementonvascularandhemodynamicparametersfollowingacuteexercise
AT soukupjeffrey theeffectsofamultiflavonoidsupplementonvascularandhemodynamicparametersfollowingacuteexercise
AT collierscottr theeffectsofamultiflavonoidsupplementonvascularandhemodynamicparametersfollowingacuteexercise
AT kappusrebeccam effectsofamultiflavonoidsupplementonvascularandhemodynamicparametersfollowingacuteexercise
AT currychelsead effectsofamultiflavonoidsupplementonvascularandhemodynamicparametersfollowingacuteexercise
AT mcanultysteve effectsofamultiflavonoidsupplementonvascularandhemodynamicparametersfollowingacuteexercise
AT welshjanice effectsofamultiflavonoidsupplementonvascularandhemodynamicparametersfollowingacuteexercise
AT morrisdavid effectsofamultiflavonoidsupplementonvascularandhemodynamicparametersfollowingacuteexercise
AT niemandavidc effectsofamultiflavonoidsupplementonvascularandhemodynamicparametersfollowingacuteexercise
AT soukupjeffrey effectsofamultiflavonoidsupplementonvascularandhemodynamicparametersfollowingacuteexercise
AT collierscottr effectsofamultiflavonoidsupplementonvascularandhemodynamicparametersfollowingacuteexercise