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Involvement of the Retinoid X Receptor Ligand in the Anti-Inflammatory Effect Induced by Peroxisome Proliferator-Activated Receptor γ Agonist In Vivo

Peroxisome proliferator-activated receptor γ (PPARγ) forms a heterodimeric DNA-binding complex with retinoid X receptors (RXRs). It has been reported that the effect of the PPAR agonist is reduced in hepatocyte RXR-deficient mice. Therefore, it is suggested that the endogenous RXR ligand is involved...

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Detalles Bibliográficos
Autores principales: Yamamoto, Atsuki, Kakuta, Hiroki, Miyachi, Hiroyuki, Sugimoto, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236425/
https://www.ncbi.nlm.nih.gov/pubmed/22190910
http://dx.doi.org/10.1155/2011/840194

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