Cargando…
Chitin, Chitinase Responses, and Invasive Fungal Infections
The human immune system is capable of recognizing and degrading chitin, an important cell wall component of pathogenic fungi. In the context of host-immune responses to fungal infections, herein we review the particular contributions and interplay of fungus and chitin recognition, and chitin-degradi...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236456/ https://www.ncbi.nlm.nih.gov/pubmed/22187561 http://dx.doi.org/10.1155/2012/920459 |
_version_ | 1782218747696644096 |
---|---|
author | Vega, Karina Kalkum, Markus |
author_facet | Vega, Karina Kalkum, Markus |
author_sort | Vega, Karina |
collection | PubMed |
description | The human immune system is capable of recognizing and degrading chitin, an important cell wall component of pathogenic fungi. In the context of host-immune responses to fungal infections, herein we review the particular contributions and interplay of fungus and chitin recognition, and chitin-degrading enzymes, known as chitinases. The mechanisms of host chitinase responses may have implications for diagnostic assays as well as novel therapeutic approaches for patients that are at risk of contracting fatal fungal infections. |
format | Online Article Text |
id | pubmed-3236456 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-32364562011-12-20 Chitin, Chitinase Responses, and Invasive Fungal Infections Vega, Karina Kalkum, Markus Int J Microbiol Review Article The human immune system is capable of recognizing and degrading chitin, an important cell wall component of pathogenic fungi. In the context of host-immune responses to fungal infections, herein we review the particular contributions and interplay of fungus and chitin recognition, and chitin-degrading enzymes, known as chitinases. The mechanisms of host chitinase responses may have implications for diagnostic assays as well as novel therapeutic approaches for patients that are at risk of contracting fatal fungal infections. Hindawi Publishing Corporation 2012 2011-12-11 /pmc/articles/PMC3236456/ /pubmed/22187561 http://dx.doi.org/10.1155/2012/920459 Text en Copyright © 2012 K. Vega and M. Kalkum. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Vega, Karina Kalkum, Markus Chitin, Chitinase Responses, and Invasive Fungal Infections |
title | Chitin, Chitinase Responses, and Invasive Fungal Infections |
title_full | Chitin, Chitinase Responses, and Invasive Fungal Infections |
title_fullStr | Chitin, Chitinase Responses, and Invasive Fungal Infections |
title_full_unstemmed | Chitin, Chitinase Responses, and Invasive Fungal Infections |
title_short | Chitin, Chitinase Responses, and Invasive Fungal Infections |
title_sort | chitin, chitinase responses, and invasive fungal infections |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236456/ https://www.ncbi.nlm.nih.gov/pubmed/22187561 http://dx.doi.org/10.1155/2012/920459 |
work_keys_str_mv | AT vegakarina chitinchitinaseresponsesandinvasivefungalinfections AT kalkummarkus chitinchitinaseresponsesandinvasivefungalinfections |