Cargando…

Protective Effects of Simvastatin, a Lipid Lowering Agent, against Oxidative Damage in Experimental Diabetic Rats

The present study was undertaken to evaluate the possible protective effects of simvastatin (SMV) against oxidative stress in streptozotocin- (STZ)-induced diabetic rats. Diabetes was induced experimentally in rats by i.p. injection of STZ in a dose of 60 mg/kg bwt. After 5 weeks of STZ injection, t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mohamadin, Ahmed M., Elberry, Ahmed A., Abdel Gawad, Hala S., Morsy, Gehan M., Al-Abbasi, Fahad A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236494/ https://www.ncbi.nlm.nih.gov/pubmed/22191036 http://dx.doi.org/10.1155/2011/167958

Ejemplares similares

Corrigendum to “Protective Effects of Simvastatin, a Lipid Lowering Agent, Against Oxidative Damage in Experimental Diabetic Rats”
por: Mohamadin, Ahmed M., et al.
Publicado: (2020)

Protective effect of bilberry (Vaccinium myrtillus) against doxorubicin-induced oxidative cardiotoxicity in rats
por: Ashour, Osama M., et al.
Publicado: (2011)

Atorvastatin and simvastatin as analgesic agents in experimental models
por: Dwajani, S., et al.
Publicado: (2012)

Simvastatin improves the eradication rate of Helicobacter pylori: upper Egypt experience
por: Hassan, Amro Metwaly, et al.
Publicado: (2019)

Molecular Lipids Identify Cardiovascular Risk and Are Efficiently Lowered by Simvastatin and PCSK9 Deficiency
por: Tarasov, Kirill, et al.
Publicado: (2014)

Judicious Use of Lipid Lowering Agents in the Management of NAFLD
por: Iqbal, Umair, et al.
Publicado: (2018)

Associations of the SLCO1B1 Polymorphisms With Hepatic Function, Baseline Lipid Levels, and Lipid-lowering Response to Simvastatin in Patients With Hyperlipidemia
por: Wu, Xiangyu, et al.
Publicado: (2018)

Genome Shuffling of Mangrove Endophytic Aspergillus luchuensis MERV10 for Improving the Cholesterol-Lowering Agent Lovastatin under Solid State Fermentation
por: El-Gendy, Mervat Morsy Abbas Ahmed, et al.
Publicado: (2016)

Simvastatin Efficiently Lowers Small LDL-IgG Immune Complex Levels: A Therapeutic Quality beyond the Lipid-Lowering Effect
por: Hörl, Gerd, et al.
Publicado: (2016)

Simvastatin, edaravone and dexamethasone protect against kainate-induced brain endothelial cell damage
por: Barna, Lilla, et al.
Publicado: (2020)

The efficacy and safety of Simvastatin in the treatment of lipid abnormalities in diabetes mellitus
por: Okeoghene, Ogbera A., et al.
Publicado: (2013)

Simvastatin attenuates radiation-induced tissue damage in mice
por: Zhao, Xinbin, et al.
Publicado: (2014)

Effects of enalapril and paricalcitol treatment on diabetic nephropathy and renal expressions of TNF-α, p53, caspase-3 and Bcl-2 in STZ-induced diabetic rats
por: Ahmed, Osama M., et al.
Publicado: (2019)

Simvastatin and Muscle: Zebrafish and Chicken Show that the Benefits are not Worth the Damage
por: Campos, Laise M., et al.
Publicado: (2022)

Simvastatin-Loaded Lipid Emulsion Nanoparticles: Characterizations and Applications
por: Ullah, Faiz, et al.
Publicado: (2022)

Rapid disintegrating tablets of simvastatin dispersions in polyoxyethylene–polypropylene block copolymer for maximized disintegration and dissolution
por: Balata, Gehan F, et al.
Publicado: (2016)

Simultaneous administration of fluoxetine and simvastatin ameliorates lipid profile, improves brain level of neurotransmitters, and increases bioavailability of simvastatin
por: Al-Asmari, Abdulrahman K, et al.
Publicado: (2017)

Novel Uses for Lipid-Lowering Agents
por: May, Megan Brafford, et al.
Publicado: (2016)

Cardiovascular disease markers in women with polycystic ovary syndrome with emphasis on asymmetric dimethylarginine and homocysteine
por: Mohamadin, Ahmed M., et al.
Publicado: (2010)

Consistency of effect of ezetimibe/simvastatin compared with intensified lipid-lowering treatment strategies in obese and non-obese diabetic subjects
por: Rosen, Jeffrey B, et al.
Publicado: (2013)

Anti-inflammatory and antiproliferative activities of date palm pollen (Phoenix dactylifera) on experimentally-induced atypical prostatic hyperplasia in rats
por: Elberry, Ahmed A, et al.
Publicado: (2011)

Immunomodulatory Effect of Red Onion (Allium cepa Linn) Scale Extract on Experimentally Induced Atypical Prostatic Hyperplasia in Wistar Rats
por: Elberry, Ahmed A., et al.
Publicado: (2014)

The first report of two monogenean gill parasites assigned to ‎Diclidophora merlangi (Diclidophoridae) and Loxuroides pricei ‎‎(Axinidae) from brushtooth lizardfish and red porgy seabream of ‎the Red Sea, Egypt
por: Morsy, Kareem, et al.
Publicado: (2018)

Discrete and continuum models of COVID-19 virus, formal solutions, stability and comparison with real data
por: Abdel-Gawad, Hamdy I., et al.
Publicado: (2021)

On a global continuum model for COVID-19 virus in the presence of vaccine and induced immunity. Stability and initial states control
por: Abdel-Gawad, Hamdy I., et al.
Publicado: (2022)

Simvastatin Evokes An Unpredicted Antagonism For Tamoxifen In MCF-7 Breast Cancer Cells
por: Ibrahim, Amel B, et al.
Publicado: (2019)

Ezetimibe in Combination With Simvastatin Reduces Remnant Cholesterol Without Affecting Biliary Lipid Concentrations in Gallstone Patients
por: Ahmed, Osman, et al.
Publicado: (2018)

Exploring simvastatin, an antihyperlipidemic drug, as a potential topical antibacterial agent
por: Thangamani, Shankar, et al.
Publicado: (2015)

Clinical-experimental assessment of simvastatin efficiency in the treatment of rheumatoid arthritis
por: Tadjikhodjaeva, Rikhikhon N, et al.
Publicado: (2012)

Experimental evaluation of analgesic and anti-inflammatory activity of simvastatin and atorvastatin
por: Jaiswal, Swapnil R., et al.
Publicado: (2012)

Bioactive Lipid Compounds as Eco-Friendly Agents in the Diets of Broiler Chicks for Sustainable Production and Health Status
por: Abdel-Wareth, Ahmed A. A., et al.
Publicado: (2023)

Hydrogel Containing Solid Lipid Nanoparticles Loaded with Argan Oil and Simvastatin: Preparation, In Vitro and Ex Vivo Assessment
por: Khan, Muhammad Farhan Ali, et al.
Publicado: (2022)

Comparison of the Treatment Efficacy of Rosuvastatin versus Atorvastatin Loading Prior to Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction
por: Adel, Esraa M., et al.
Publicado: (2022)

Persistence With Lipid-Lowering Therapy: Influence of the Type of Lipid-Lowering Agent and Drug Benefit Plan Option in Elderly Patients
por: Abughosh, Susan M., et al.
Publicado: (2004)

Formulation and evaluation of simvastatin cubosomal nanoparticles for assessing its wound healing effect
por: Ahmed, Lamiaa M., et al.
Publicado: (2023)

Role of lipid-lowering agents in the management of diabetic retinopathy
por: Ioannidou, Estelle, et al.
Publicado: (2017)

Formulation and Evaluation of Nanocrystals of a Lipid Lowering Agent
por: Louis, Dina
Publicado: (2016)

Statins and the Brain: More than Lipid Lowering Agents?
por: Fracassi, Anna, et al.
Publicado: (2019)

Evaluation of tamoxifen and simvastatin as the combination therapy for the treatment of hormonal dependent breast cancer cells
por: Ibrahim, Amel B., et al.
Publicado: (2019)

Synergistic effect of simvastatin and ezetimibe on lipid and pro-inflammatory profiles in pre-diabetic subjects
por: Kater, Ana-Lucia A, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_ggtn9mtdolu1a69cieqrg53gbp