Effects of Selected Anionic β-Cyclodextrins on Persistence of Blood Glucose Lowering by Insulin Glargine after Subcutaneous Injection to Rats

Insulin glargine is a synthetic long-acting insulin product used for patients with diabetes mellitus. In this study, to obtain the further desirable blood-glucose lowering profile of insulin glargine, we investigated the effects of β-cyclodextrin sulfate (Sul-β-CyD) and sulfobutylether β-cyclodextri...

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Detalles Bibliográficos
Autores principales: Uehata, Keiko, Anno, Takayuki, Hayashida, Kayoko, Motoyama, Keiichi, Higashi, Taishi, Hirayama, Fumitoshi, Ono, Naomi, Pipkin, James D., Uekama, Kaneto, Arima, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236511/
https://www.ncbi.nlm.nih.gov/pubmed/22187651
http://dx.doi.org/10.1155/2011/195146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236511/
https://www.ncbi.nlm.nih.gov/pubmed/22187651
http://dx.doi.org/10.1155/2011/195146

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