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Neuroprotective effects of Tacrolimus (FK-506) and Cyclosporin (CsA) in oxidative injury

The detrimental effects of hypoxic damage to central nervous system lead to energy depletion, free radical formation, lipid peroxidation (LPO), and increased calcium. We hypothesized that in vitro tacrolimus (FK-506) and cyclosporine A (CsA) could be protective against hypoxic damage in spinal cord....

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Detalles Bibliográficos
Autores principales: Yousuf, Seema, Atif, Fahim, Kesherwani, Varun, Agrawal, Sandeep Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Inc 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236540/
https://www.ncbi.nlm.nih.gov/pubmed/22399088
http://dx.doi.org/10.1002/brb3.16